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Jeffrey Esko
Jeffrey David Esko, Ph.D.,M.D. (h.c) is currently a Full Professor of Cellular and Molecular Medicine〔http://cmm.ucsd.edu/〕 and Co-Director of the Glycobiology Research and Training Center〔http://grtc.ucsd.edu/〕 at the University of California, San Diego. His research has focuses on understanding the structure, biosynthesis and biological roles of proteoglycans in mammalian cells and model organisms. Esko popularized〔http://www.glycobiology.org/winner-2007-karl.php〕 proteoglycans through his pioneering genetic and functional studies in cells and model organisms. He discovered the dependence of tumor formation on heparan sulfate, the first small molecule inhibitors of heparan sulfate, the action of proteoglycans as receptors for hepatic lipoprotein clearance and for delivery of therapeutic agents. Esko cofounded Zacharon Pharmaceuticals.〔http://investing.businessweek.com/research/stocks/private/person.asp?personId=50880313&privcapId=50090251&previousCapId=50090251&previousTitle=Zacharon%20Pharmaceuticals,%20Inc.〕 He was an editor and author of the first textbook in the Glycobiology field, Essentials of Glycobiology.〔Varki A, Cummings RD, Esko JD, et al., editors. Essentials of Glycobiology. 2nd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2009. Available from: http://www.ncbi.nlm.nih.gov/books/NBK1908/〕
==Education==
Esko received his Ph.D.in Biochemistry at the University of Wisconsin in Madison. After an independent fellowship at the Molecular Biology Institute at the University of California,Los Angeles, he moved to the University of Alabama at Birmingham and then to the Department of Cellular and Molecular Medicine at the University of California, San Diego in 1996 to help build a program in Glycobiology. He has published over 250 scholarly papers, reviews and book chapters and was editor/author of the first textbook in the field, Essentials of Glycobiology (1st and 2nd editions).〔〔 The 2nd edition of Essentials of Glycobiology is made freely available online and became one of the pioneering textbooks to be distributed electronically.〔McEntyre J, Lipman D. Foreword. In: Varki A, Cummings RD, Esko JD, et al., editors. Essentials of Glycobiology. 2nd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2009. Available from: http://www.ncbi.nlm.nih.gov/books/NBK1918/〕〔http://dev.biologists.org/content/136/24/4072.full〕
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